RNA Editing Catalogue Of Diverse Eukarya Database (RECODE) is an interactive database built with the aim to allocate RNA editing events (e.g., A-to-I and C-to-U RNA editing) occurring in a wide range of organisms. The database contains genome-wide editing information which is available either by experimental inspection (in vitro or in vivo) or by computational detection (in silico). Each record of RECODE is organized in the context of evolution containing a description of the main characteristics of the entry, a feature table of the editing event with related details and sequence contexts including both the genomic sequence (DNA) and the corresponding edited transcript (RNA). RECODE is a relational database in which the visualization and web-based interaction of editing sites has been simplified by means of two facilities to either graphically display genomic or cDNA tags (e.g., ESTs and NGS short reads) or to show the sequence type of genomic content (e.g., repetitive elements), RNA secondary structure, as well as cross-species sequence alignment. In both instances, the editing sites in a specific genic region are highlighted and embedded with cDNA reads from NGS experiments in different biological conditions, and their pre-computed structural and sequence features are visualized in a ‘transcriptome-aware’ context. New editing positions will be regularly updated to RECODE after manual annotation to keep the quality of information. This first version of RECODE database stores 1.5 million editing events in 21 diverse species, from human to C. elegant, and can be freely queried at http://red.genomics.sinica.edu.tw.